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Hanayama Lab

Exosome functions and clinical applications

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03/2025
Our paper on the direct delivery of immune modulators to tumour-infiltrating lymphocytes using engineered extracellular vesicles has been published in J Extracell Vesicles.
03/2025
A collaborative paper on nanoscopic profiling of small extracellular vesicles via AFM has been published in J Extracell Vesicles.
02/2025
A collaborative paper on the direct extraction and evaluation of intraluminal vesicles inside a cell has been published in Nano Lett.
02/2025
A book on Extracellular Fine Particles has been published by Springer.
09/2024
Our paper identifying fibrinogen as an inflammatory ligand for LILRA2 has been published hed in Front Immunol.
08/2024
A collaborative research paper on exosome biogenesis by an autophagy-related factor has been published in Nat Cell Biol.
08/2024
Our review paper on quality and safety considerations for EV-therapeutic products has been published in Pharm Res.
05/2024
Our paper identifying a new hybid gene LILRB5-3 has been published in Front Immunol.
05/2024
A collaborative paper finding a mechanism by which denderitic cells activate T cells via extracellular vesicles has been published in iScience.
03/2024
Our paper developing a precise analytical method of single extracellular vesicles using flow cytometry has been published in Sci Rep.
03/2024
Our paper showing protective effect of exosomes on silica-induced cytotoxicity has been published in Arch Biochem Biophys.
01/2024
MassivEV is now available for high-purity large-scale isolation of EVs.
11/2023
A collaborative research paper identifying a novel mechanism by which exosomes create a pro-metastatic microenviroment has been published in Int J Cancer.
09/2023
Our preprint manuscript on engineered EVs that modulate antigen-specific anti-tumor immunity has been posted on bioRxiv.
08/2023
A collaborative research paper unveiling the nanodynamics of extracellular vesicle has been published in Anal Chem.
04/2023
A collaborative research paper that validated the utility of serum microRNA as a marker of osteosarcoma has been published in Oncol Lett.


大阪大学免疫学フロンティア研究センター 免疫ネットProf. HANAYAMA Rikinari
13-1 Takara, Kanazawa, Ishikawa 920-8640, JAPAN
TEL +81-76-265-2725
hanayamamed.kanazawa-u.ac.jp